Bipolar Disorder Research Center

Active Studies

Neurodevelopmental and Clinical Trajectories of Youth at Risk for Bipolar I Disorder

The goals of the research are to better understand brain development underlying risk for bipolar disorder by using longitudinal neuroimaging to identify the neurophysiological and clinical predictors of emerging illness in youth with parental risk for bipolar disorder.

Oxygenating the Brain with Laser Stimulation Therapy to Improve Cognitive Function in Bipolar Disorder

To rigorously test Transcranial Infra-red Laser Stimulation as a novel, non-invasive, and non-pharmacologic intervention for cognitively impaired individuals with bipolar disorder.

The Cost of Bipolar Disorder Misdiagnosis and Associated Savings with a Specialized Program Model

To screen for bipolar disorder illness in the UT Austin and UT Administration and treat using the 6-week program model in the bipolar disorder center.

Familial Risk for Bipolar Disorder and Alcohol Sensitivity

To use alcohol administration procedures and alcohol biosensor technology to investigate responses to alcohol, compared to placebo, and relationship with parental risk for alcohol use disorders and/or bipolar disorder in young adults.

Stress, Suicide, and Bipolar Disorder Neuroimaging Study

To investigate neural correlates of suicide attempts in young adults with bipolar disorder.

Longitudinal Bipolar Alcohol Consumption Study

Investigators are studying experiences of alcohol intoxication and related brain development and behavior during young adulthood. The purpose of the study is to investigate how the brain responds to alcohol overtime and related brain changes in bipolar disorder and compare these effects among individuals who do not have bipolar disorder.

Focused Ultrasound Amygdala Neuromodulation for the Mechanistic Treatment of Affective Disorders

To examine the feasibility and potential efficacy of ultrasound as a method of modulating amygdala function to promote improvements in symptoms of an affective disorder.

Recruitment Starting Soon

Closed Studies

Leveraging a Collaborative Network to Test TMS treatment for Bipolar Depression

To build a framework for collaborative TMS studies in bipolar depression guided by neuroimaging and neuronavigation using the Stanford Neuromodulation Treatment protocol.

A Randomized, Double-Blind Controlled Comparison of NRX-101 to Lurasidone for Adults with Bipolar Depression and Subacute Suicidal Ideation or Behavior

To determine whether patients with Severe Bipolar Depression and subacute Suicidal Ideation or Behavior (i.e. those not requiring inpatient care) can be treated effectively with NRX-101.

A Randomized, Stratified, Double-blind, Placebo-Controlled Study to Investigate the Efficacy, Safety and Tolerability of JNJ-55308942 in Bipolar Depression

To evaluate the efficacy of an investigational medication compared to placebo on symptoms of depression in participants with bipolar disorder in a major depressive episode.